Original paper
Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy
Abstract
The pattern recognition receptor RIG-I plays an important role in the recognition of nonself RNA and antiviral immunity. RIG-I's natural ligand, triphosphate RNA (ppp-RNA), is proposed to be a valuable addition to the growing arsenal of cancer immunotherapy treatment options. In this study, we present comprehensive data validating the concept and utility of treatment with synthetic RIG-I agonist ppp-RNA for the therapy of human cancer, with...
Paper Details
Title
Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy
Published Date
Dec 1, 2019
Volume
18
Issue
12
Pages
2343 - 2356
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Notes
History