Assessment of mesenchymal stem cell effect on foreign body response induced by intraperitoneally implanted alginate spheres

Foreign body response to implanted hydrogels and consequently fibrotic overgrowth on implanted spheres will decrease in vivo performance of these biomaterials. Considering the previous reports related to the immune‐privileged properties of mesenchymal stem cells (MSCs), we hypothesized that encapsulated human placenta‐derived MSCs (HP‐MSCs) will mitigate the foreign body response against alginate hydrogels. The HP‐MSC‐laden alginate hydrogel was...