Mechanisms and Evidence for Heart Failure Benefits from SGLT2 Inhibitors
Abstract
To review the clinical trial data and underlying mechanistic principles in support of the robust cardiovascular (CV) benefits, in particular, heart failure (HF) outcomes association with sodium-glucose co-transporter-2 (SGLT2) inhibitors. Several large CV outcome trials in patients with type 2 diabetes mellitus (T2DM) and with either established atherosclerotic CV disease (ASCVD) or at high risk for ASCVD reveal that SGLT2 inhibitors cause...
Paper Details
Title
Mechanisms and Evidence for Heart Failure Benefits from SGLT2 Inhibitors
Published Date
Sep 14, 2019
Journal
Volume
21
Issue
10
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