Original paper
Two CRISPR/Cas9-mediated methods for targeting complex insertions, deletions, or replacements in mouse
Abstract
Genetically modified model organisms are valuable tools for probing gene function, dissecting complex signaling networks, studying human disease, and more. CRISPR/Cas9 technology has significantly democratized and reduced the time and cost of generating genetically modified models to the point that small gene edits are now routinely and efficiently generated in as little as two months. However, generation of larger and more sophisticated...
Paper Details
Title
Two CRISPR/Cas9-mediated methods for targeting complex insertions, deletions, or replacements in mouse
Published Date
Jan 1, 2019
Journal
Volume
6
Pages
2088 - 2100
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Notes
History