Altered motor, anxiety-related and attentional task performance at baseline associate with multiple gene copies of the vesicular acetylcholine transporter and related protein overexpression in ChAT::Cre+ rats
Abstract
Transgenic rodents expressing Cre recombinase cell specifically are used for exploring mechanisms regulating behavior, including those mediated by cholinergic signaling. However, it was recently reported that transgenic mice overexpressing a bacterial artificial chromosome containing choline acetyltransferase ( ChAT ) gene, for synthesizing the neurotransmitter acetylcholine, present with multiple vesicular acetylcholine transporter ( VAChT )...
Paper Details
Title
Altered motor, anxiety-related and attentional task performance at baseline associate with multiple gene copies of the vesicular acetylcholine transporter and related protein overexpression in ChAT::Cre+ rats
Published Date
Sep 10, 2019
Journal
Volume
224
Issue
9
Pages
3095 - 3116
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