The cardiovascular phenotype of adult patients with phenylketonuria

Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown. The purpose of this study was to characterize the cardiovascular phenotype in adult patients with PKU by clinical and dietary data, measurements of biochemical markers, and non-invasive examination of vascular functions. Twenty-three adult patients with PKU (age: 18–47 y; 30.8 ± 8.4 y) and...