Release of doxorubicin from its liposomal coating via high intensity ultrasound
Abstract
The present ex vivo study was performed to analyze the impact of high intensity ultrasound (HIUS) on penetration depth and particle stability of liposomal doxorubicin (LD) on the peritoneal surface. Fresh post mortem swine peritoneum was cut into proportional sections and subjected to a previously established ex vivo model of pressurized intraperitoneal aerosol chemotherapy (PIPAC). Samples were treated with 50 ml NaCl (0.9%) containing 3 mg LD...
Paper Details
Title
Release of doxorubicin from its liposomal coating via high intensity ultrasound
Published Date
Sep 5, 2019
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