Reversal of epigenetic aging and immunosenescent trends in humans
Abstract
Epigenetic “clocks” can now surpass chronological age in accuracy for estimating biological age. Here, we use four such age estimators to show that epigenetic aging can be reversed in humans. Using a protocol intended to regenerate the thymus, we observed protective immunological changes, improved risk indices for many age‐related diseases, and a mean epigenetic age approximately 1.5 years less than baseline after 1 year of treatment (−2.5‐year...
Paper Details
Title
Reversal of epigenetic aging and immunosenescent trends in humans
Published Date
Sep 8, 2019
Journal
Volume
18
Issue
6
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