Pediatric NUT Carcinoma Is a Rare and Challenging Tumor: Single Center Experience of Five Children

Background Nuclear protein of the testis (NUT) carcinoma is a rare and aggressive malignancy associated with rearrangements of the nuclear protein of the testis (NUT) gene on chromosome 15q14. Because of its rarity, this tumor is often underdiagnosed and underreported, and there is limited literature regarding its biology and optimal management. Methods and Results We report our experience of five patients with pediatric NUT carcinoma, all of...