Abstract P3005: P66shc Plays a Role in Aldosterone Induced Vascular Remodeling and Dysfunction
Abstract
Objective: This study sought to investigate whether aldosterone may induce vascular functional and structural alterations in part through p66shc-dependent processes. Design and method: P66shc -/- mice (14 weeks, 6 per group) and age-matched wild type (WT) control mice were treated or not with aldosterone (300 μg /kg/ day) for 4 weeks. Systolic blood pressure (SBP) was measured by tail-cuff method. Endothelium-dependent and independent relaxation...
Paper Details
Title
Abstract P3005: P66shc Plays a Role in Aldosterone Induced Vascular Remodeling and Dysfunction
Published Date
Sep 1, 2019
Journal
Volume
74
Issue
Suppl_1
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