Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening
Abstract
Lung cancer shows substantial genetic and phenotypic heterogeneity across individuals, driving a need for personalised medicine. Here, we report lung cancer organoids and normal bronchial organoids established from patient tissues comprising five histological subtypes of lung cancer and non-neoplastic bronchial mucosa as in vitro models representing individual patient. The lung cancer organoids recapitulate the tissue architecture of the primary...
Paper Details
Title
Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening
Published Date
Sep 5, 2019
Journal
Volume
10
Issue
1
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