A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials
Abstract
Large longitudinal biomarkers database focusing on middle age is needed for Alzheimer's disease (AD) prevention.Data for cerebrospinal fluid analytes, molecular imaging of cerebral fibrillar β-amyloid with positron emission tomography, magnetic resonance imaging-based brain structures, and clinical/cognitive outcomes were harmonized across eight AD biomarker studies. Statistical power was estimated.The harmonized database included 7779...
Paper Details
Title
A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials
Published Date
Sep 7, 2019
Journal
Volume
15
Issue
11
Pages
1448 - 1457
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