Differential expression of miRNAs regulating NF-κB and STAT3 crosstalk during colitis-associated tumorigenesis
Abstract
Inflammatory bowel disease (IBD) is mostly responsible for the development of colitis-associated colon cancer. Of the several signaling pathways involved in colonic inflammation, the activation and crosstalk between NF-κB and STAT3 serve as the pivotal regulatory hubs that regulate epithelial tumorigenesis by linking inflammation with cancer development. Understanding the molecular mechanisms regulating the crosstalk between NF-κB and STAT3 will...
Paper Details
Title
Differential expression of miRNAs regulating NF-κB and STAT3 crosstalk during colitis-associated tumorigenesis
Published Date
Oct 1, 2019
Volume
47
Pages
101442 - 101442
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