Review paper
Glutathione transferase genotypes may serve as determinants of risk and prognosis in renal cell carcinoma
Volume: 46, Issue: 2, Pages: 229 - 238
Published: Sep 4, 2019
Abstract
Renal cell carcinoma (RCC) represents a group of histologically similar neoplasms with significant intratumor and intertumor genetic heterogeneity. Recognized risk factors for RCC development include smoking, hypertension, obesity, as well as von Hippel–Lindau (VHL) disease. Inactivation of VHL, deregulated nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) pathway, and altered redox homeostasis, together with changes in glutathione transferase...
Paper Details
Title
Glutathione transferase genotypes may serve as determinants of risk and prognosis in renal cell carcinoma
Published Date
Sep 4, 2019
Volume
46
Issue
2
Pages
229 - 238
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