Original paper
Fate‐mapping analysis using Rorb‐IRES‐Cre reveals apical‐to‐basal gradient of Rorb expression in mouse cochlea
Abstract
Background Conditional loss‐of‐function studies are widely conducted using the Cre/Loxp system because this helps circumvent embryonic or neonatal lethality problems. However, Cre strains specific to the inner ear are lacking, and thus lethality frequently occurs even in conditional knockout studies. Results Here, we report a Rorb‐IRES‐Cre knockin mouse strain in which the Cre recapitulates the expression pattern of endogenous Rorb (RAR‐related...
Paper Details
Title
Fate‐mapping analysis using Rorb‐IRES‐Cre reveals apical‐to‐basal gradient of Rorb expression in mouse cochlea
Published Date
Oct 14, 2019
Journal
Volume
249
Issue
2
Pages
173 - 186
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Notes
History