Slow degrading hyaluronic acid hydrogel reinforced with cationized graphene nanosheets

Graphene possesses a large surface area and offers high loading capacity for aromatic compounds. However, the load is quickly released in the absence of rate limiting diffusion barrier. In this study, we have explored the electrostatic interaction between polyanionic hyaluronic acid (HA) and cationized reduced graphene oxide (rGO) as a means to develop a reinforced hydrogel matrix. We tested if; (i) degradation kinetics of HA matrix can be...