Glycolysis dependent lactate formation in neutrophils: A metabolic link between NOX-dependent and independent NETosis

Volume: 1865, Issue: 12, Pages: 165542 - 165542
Published: Dec 1, 2019
Abstract
Neutrophil extracellular traps (NETs) play a pivotal role in the innate immune defense, as well as in the pathophysiology of various inflammatory disease conditions. Two major types of NETosis have been described - NOX-dependent and independent. The present study was undertaken to assess metabolic requirements of NETs formation by using PMA and A23187 as the inducers of NOX-dependent and NOX-independent NETosis respectively. Both these inducers...
Paper Details
Title
Glycolysis dependent lactate formation in neutrophils: A metabolic link between NOX-dependent and independent NETosis
Published Date
Dec 1, 2019
Volume
1865
Issue
12
Pages
165542 - 165542
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