An analysis of genetic heterogeneity in untreated cancers
Abstract
Genetic intratumoural heterogeneity is a natural consequence of imperfect DNA replication. Any two randomly selected cells, whether normal or cancerous, are therefore genetically different. Here, we review the different forms of genetic heterogeneity in cancer and re-analyse the extent of genetic heterogeneity within seven types of untreated epithelial cancers, with particular regard to its clinical relevance. We find that the homogeneity of...
Paper Details
Title
An analysis of genetic heterogeneity in untreated cancers
Published Date
Aug 27, 2019
Journal
Volume
19
Issue
11
Pages
639 - 650
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