The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
Abstract
Apart from amyloid β deposition and tau neurofibrillary tangles, Alzheimer's disease (AD) is a neurodegenerative disorder characterized by neuronal loss and astrocytosis in the cerebral cortex. The goal of this study is to investigate genetic factors associated with the neuronal proportion in health and disease. To identify cell-autonomous genetic variants associated with neuronal proportion in cortical tissues, we inferred cellular population...
Paper Details
Title
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
Published Date
Aug 27, 2019
Journal
Volume
139
Issue
1
Pages
45 - 61
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