MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling
Abstract
This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli.Macrophage-specific Dicer knockout (KO) mice were used to determine the roles of microRNA generated in macrophages in adipose tissue remodeling induced by the β3-adrenergic receptor agonist CL316,243 (CL). RNA-seq was performed to characterize microRNA and mRNA...
Paper Details
Title
MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling
Published Date
Nov 1, 2019
Journal
Volume
29
Pages
86 - 98
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Notes
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