Small size apolipoprotein(a) isoforms enhance inflammatory and proteolytic potential of collagen-primed monocytes
Abstract
Atherosclerosis is an inflammatory process involving activation of monocytes recruited by various chemoattractant factors, among which lipoprotein(a) and its specific apolipoprotein apo(a). Lp(a) contains a specific apolipoprotein apo(a) which size is determined by a variable number of repeats of a specific structural domain, the kringle IV type 2 (IV-2). Lp(a) plasma concentration and apo(a) size is inversely correlated, and smaller apo(a) are...
Paper Details
Title
Small size apolipoprotein(a) isoforms enhance inflammatory and proteolytic potential of collagen-primed monocytes
Published Date
Aug 31, 2019
Journal
Volume
18
Issue
1
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