Imaging at the inter-face of inflammation and angiogenesis by ¹⁸F-fluciclatide PET

Mechanisms underlying atherosclerotic plaque rupture are complex and unpredictable by any current imaging test. However, several key pathogenic processes known to increase the likelihood of an acute plaque event can be tracked in vivo using positron emission tomography (PET). In their Heart paper, Jenkins et al 1 examine the utility of 18F-fluciclatide, an αvβ3integrin-binding PET tracer, for imaging atherosclerosis. This intriguing study adds...