Staphylococcal superantigen‐like proteins interact with human MAP kinase signaling protein ERK2

Volume: 594, Issue: 2, Pages: 266 - 277
Published: Sep 11, 2019
Abstract
This study aimed to identify the intracellular binding partner of a unique class of staphylococcal secreted exotoxins called superantigen-like proteins (SSL) from human macrophage and keratinocyte cell lysates. Here, we report that SSL1 specifically binds to human extracellular signal-regulated kinase 2 (hERK2), an important stress-activated kinase in mitogen-activated protein kinase signaling pathways. Western blot and in vitro binding studies...
Paper Details
Title
Staphylococcal superantigen‐like proteins interact with human MAP kinase signaling protein ERK2
Published Date
Sep 11, 2019
Volume
594
Issue
2
Pages
266 - 277
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