Original paper
Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore
Abstract
Background Despite significant endeavor having been applied to identify effective therapies to treat glioblastoma (GBM), survival outcomes remain intractable. The greatest nonsurgical benefit arises from radiotherapy, though tumors typically recur due to robust DNA repair. Patients could therefore benefit from therapies with the potential to prevent DNA repair and synergize with radiotherapy. In this work, we investigated the potential of...
Paper Details
Title
Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore
Published Date
Aug 30, 2019
Journal
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Notes
History