A benefit-risk analysis of pegvaliase for the treatment of phenylketonuria: A study of patients' preferences
Abstract
Phenylketonuria (PKU) leads to an accumulation of phenylalanine (Phe) in the blood and subsequent neurologic, cognitive, psychiatric, and behavioral dysfunction. Many patients report social isolation and decreased quality of life. Pegvaliase is an enzyme substitution therapy that reduces blood Phe levels in patients with PKU and is associated with a risk of hypersensitivity reactions.To define the minimum acceptable benefit (MAB) of pegvaliase,...
Paper Details
Title
A benefit-risk analysis of pegvaliase for the treatment of phenylketonuria: A study of patients' preferences
Published Date
Dec 1, 2019
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History