Role of Angiogenesis and Chronic Inflammation in Fat Hypertrophy in NASH Pathology

Volume: 139, Issue: 9, Pages: 1163 - 1167
Published: Sep 1, 2019
Abstract
Tissue expansion and chronic inflammation in adipose tissue (AT) are closely related to nonalcoholic steatohepatitis (NASH) pathology. Angiogenesis is initiated by the detachment of pericytes (PCs) from vessels in AT. This process is necessary for the development of AT in obesity. The detachment is caused by excessive platelet-derived growth factor B (PDGF-B) derived from M1-macrophages (Mφ) infiltrating obese AT. On the other hand, AT of...
Paper Details
Title
Role of Angiogenesis and Chronic Inflammation in Fat Hypertrophy in NASH Pathology
Published Date
Sep 1, 2019
Volume
139
Issue
9
Pages
1163 - 1167
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