Δ 8 ‐Tetrahydrocannabivarin has potent anti‐nicotine effects in several rodent models of nicotine dependence
Volume: 176, Issue: 24, Pages: 4773 - 4784
Published: Oct 28, 2019
Abstract
Background and Purpose Both types of cannabinoid receptors—CB 1 and CB 2 —regulate brain functions relating to addictive drug‐induced reward and relapse. CB 1 receptor antagonists and CB 2 receptor agonists have anti‐addiction efficacy, in animal models, against a broad range of addictive drugs. Δ 9 ‐Tetrahydrocannabivarin (Δ 9 ‐THCV)—a cannabis constituent—acts as a CB 1 antagonist and a CB 2 agonist. Δ 8 ‐Tetrahydrocannabivarin (Δ 8 ‐THCV) is...
Paper Details
Title
Δ 8 ‐Tetrahydrocannabivarin has potent anti‐nicotine effects in several rodent models of nicotine dependence
Published Date
Oct 28, 2019
Volume
176
Issue
24
Pages
4773 - 4784
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