When time's arrow doesn't bend: APOE-ε4 influences episodic memory before old age

Episodic memory impairment is the hallmark symptom of Alzheimer's Disease (AD). However, episodic memory has also been shown to decline across the lifespan. Here, we investigated whether episodic memory is differentially affected relative to other cognitive abilities before old age, and whether being an Apolipoprotein E (APOE) ε4 carrier –a genetic risk factor for developing AD—exacerbates any such impairments. We used general linear models to...