KRAS Status as a Predictor of Chemotherapy Activity in Patients With Metastatic Colorectal Cancer
Abstract
Background: KRAS mutations occur in 40% of colorectal cancers (CRCs), affecting the efficacy of agents targeting the epidermal growth factor receptor. However, the effect of KRAS mutation status on the activity of non-epidermal growth factor receptor-targeting chemotherapy has not been fully elucidated. The aim of the present study is to evaluate the effect of KRAS status on the activity of different chemotherapeutic regimens. Patients and...
Paper Details
Title
KRAS Status as a Predictor of Chemotherapy Activity in Patients With Metastatic Colorectal Cancer
Published Date
Dec 1, 2019
Journal
Volume
18
Issue
4
Pages
e309 - e315
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