Simplified adenine base editors improve adenine base editing efficiency in rice

Summary Adenine base editors ( ABE s) have been exploited to introduce targeted adenine (A) to guanine (G) base conversions in various plant genomes, including rice, wheat and Arabidopsis . However, the ABE s reported thus far are all quite inefficient at many target sites in rice, which hampers their applications in plant genome engineering and crop breeding. Here, we show that unlike in the mammalian system, a simplified base editor ABE ‐P1S...