Oral administration of recombinant Bacillus subtilis spores expressing Helicobacter pylori neutrophil‐activating protein suppresses peanut allergy via up‐regulation of Tregs
Volume: 49, Issue: 12, Pages: 1605 - 1614
Published: Sep 12, 2019
Abstract
Background Helicobacter pylori neutrophil-activating protein (NAP) is an immune modulator with anti-Th2 inflammation activity that can be used to prevent IgE-mediated allergic reactions. Cholera toxin B (CTB) is a mucosal adjuvant that can induce antigen tolerance. Bacillus subtilis spores are an ideal vehicle for the oral delivery of heterologous antigens. Objective We investigated the therapeutic effect of recombinant NAP B subtilis spores on...
Paper Details
Title
Oral administration of recombinant Bacillus subtilis spores expressing Helicobacter pylori neutrophil‐activating protein suppresses peanut allergy via up‐regulation of Tregs
Published Date
Sep 12, 2019
Volume
49
Issue
12
Pages
1605 - 1614
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