Umbrella and basket trials in oncology: ethical challenges
Abstract
Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referred to scientific validity, risk-benefit balance and informed consent. Our aim is to discuss these issues in basket and umbrella trials, giving examples of two ongoing cancer trials: NCI-MATCH (National Cancer Institute - Molecular Analysis...
Paper Details
Title
Umbrella and basket trials in oncology: ethical challenges
Published Date
Aug 23, 2019
Journal
Volume
20
Issue
1
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