Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
Abstract
Meiosis is the specialized cell division during which parental genomes recombine to create genotypically unique gametes. Despite its importance, mammalian meiosis cannot be studied in vitro, greatly limiting mechanistic studies. In vivo, meiocytes progress asynchronously through meiosis and therefore the study of specific stages of meiosis is a challenge. Here, we describe a method for isolating pure sub-populations of nuclei that allows for...
Paper Details
Title
Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
Published Date
Aug 23, 2019
Journal
Volume
10
Issue
1
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