Pheno-seq – linking visual features and gene expression in 3D cell culture systems
Abstract
Patient-derived 3D cell culture systems are currently advancing cancer research since they potentiate the molecular analysis of tissue-like properties and drug response under well-defined conditions. However, our understanding of the relationship between the heterogeneity of morphological phenotypes and the underlying transcriptome is still limited. To address this issue, we here introduce “pheno-seq” to directly link visual features of 3D cell...
Paper Details
Title
Pheno-seq – linking visual features and gene expression in 3D cell culture systems
Published Date
Aug 26, 2019
Journal
Volume
9
Issue
1
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