P4.33: Operational tolerance can be achieved after intestinal transplant: first report and mechanistic analysis

Introduction: Transplantation tolerance is a highly sought and rarely achieved state in clinical medicine. Defined as long-term stable and acceptable graft tolerance without immunosuppression and with an otherwise competent immune system, tolerance maximizes graft survival and function and decreases organ demand without the negative side effects of immunosuppression. While there have been prior reports of tolerance after liver and kidney...