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Geographical Variation and Factors Associated With Inflammatory Bowel Disease in a Central Canadian Province

Published on Aug 23, 2019in Inflammatory Bowel Diseases4.005
· DOI :10.1093/ibd/izz168
Mahmoud Torabi10
Estimated H-index: 10
(UM: University of Manitoba),
Charles N. Bernstein82
Estimated H-index: 82
(UM: University of Manitoba)
+ 3 AuthorsHarminder Singh29
Estimated H-index: 29
(UM: University of Manitoba)
Abstract
  • References (15)
  • Citations (1)
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References15
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#1Shailja C. Shah (VUMC: Vanderbilt University Medical Center)H-Index: 9
#2Hamed Khalili (Harvard University)H-Index: 24
Last. Jean-Frederic Colombel (Mount Sinai Hospital)H-Index: 129
view all 28 authors...
Background & Aims Although the incidence of inflammatory bowel diseases (IBDs) varies with age, few studies have examined variations between the sexes. We therefore used population data from established cohorts to analyze sex differences in IBD incidence according to age at diagnosis. Methods We identified population-based cohorts of patients with IBD for which incidence and age data were available (17 distinct cohorts from 16 regions of Europe, North America, Australia, and New Zealand). We col...
18 CitationsSource
#1Siew C. Ng (CUHK: The Chinese University of Hong Kong)H-Index: 50
#2Hai Yun Shi (CUHK: The Chinese University of Hong Kong)H-Index: 7
Last. Gilaad G. Kaplan (U of C: University of Calgary)H-Index: 49
view all 12 authors...
Summary Background Inflammatory bowel disease is a global disease in the 21st century. We aimed to assess the changing incidence and prevalence of inflammatory bowel disease around the world. Methods We searched MEDLINE and Embase up to and including Dec 31, 2016, to identify observational, population-based studies reporting the incidence or prevalence of Crohn's disease or ulcerative colitis from 1990 or later. A study was regarded as population-based if it involved all residents within a speci...
414 CitationsSource
#1Eric I. BenchimolH-Index: 31
#2David R. Mack (U of O: University of Ottawa)H-Index: 51
Last. Douglas G. Manuel (U of O: University of Ottawa)H-Index: 35
view all 8 authors...
Inflammatory Bowel Disease in Immigrants to Canada And Their Children: A Population-Based Cohort Study
92 CitationsSource
#1Desmond Leddin (Dal: Dalhousie University)H-Index: 16
#2Hala Tamim (Dal: Dalhousie University)H-Index: 37
Last. Adrian R. Levy (Dal: Dalhousie University)H-Index: 39
view all 3 authors...
Background Nova Scotia has one of the highest incidences of inflammatory bowel disease (IBD) in the world. We wished to determine trends of IBD over time.
30 CitationsSource
#1Eric I. BenchimolH-Index: 31
#2Douglas G. ManuelH-Index: 35
Last. David R. Mack (Children's Hospital of Eastern Ontario)H-Index: 51
view all 7 authors...
83 CitationsSource
#1Alain Bitton (McGill University)H-Index: 27
#2Maria Vutcovici (MUHC: McGill University Health Centre)H-Index: 8
Last. Paul Brassard (McGill University)H-Index: 31
view all 6 authors...
33 CitationsSource
#1Mahmoud Torabi (UM: University of Manitoba)H-Index: 10
In spatial epidemiology, detecting areas with high ratio of disease is important as it may lead to identifying risk factors associated with disease. This in turn may lead to further epidemiological investigations into the nature of disease. Disease mapping studies have been widely performed with considering only one disease in the estimated models. Simultaneous modelling of different diseases can also be a valuable tool both from the epidemiological and also from the statistical point of view. I...
5 CitationsSource
BACKGROUND: Inflammatory bowel diseases (IBD) – Crohn’s disease (CD) and ulcerative colitis (UC) – significantly impact quality of life and account for substantial costs to the health care system and society.
157 CitationsSource
#1Mahmoud Torabi (UM: University of Manitoba)H-Index: 10
#2Rhonda J. Rosychuk (U of A: University of Alberta)H-Index: 22
In this article, generalized additive mixed models are constructed for the analysis of geographical and temporal variability of cancer ratios. In this class of models, spatially correlated random effects and temporal components are adopted. Spatio-temporal models that use intrinsic conditionally autoregressive smoothing across the spatial dimension and B-spline smoothing over the temporal dimension are considered. We study the patterns of incidence ratios over time and identify areas with consis...
17 CitationsSource
#2Lawrence Elliott (UM: University of Manitoba)H-Index: 23
Last. Charles N. Bernstein (UM: University of Manitoba)H-Index: 82
view all 4 authors...
The authors’ objective in this study was to determine geographic variations in the incidence of inflammatory bowel disease (IBD), specifically Crohn’s disease and ulcerative colitis, in the Canadian province of Manitoba and its association with the sociodemographic, geographic, and disease-related characteristics of the study population. Using the University of Manitoba IBD Epidemiology Database, the authors applied spatial and ecologic techniques to visualize, explore, and model the incidence o...
112 CitationsSource
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