Optimizing HLA-antibody Determination

E.J.F. and M.H.R. participated in the writing of the letter. We read with great interest the paper in Transplantation by Bertrand et al1 comparing the sensitivity and specificity of Labscreen (One Lambda) versus Lifecodes (Immucor) beadsets for determination of donor specific human leukocyte antigen (HLA) antibodies following kidney transplantation. Indeed, our work clarifies to some extent their findings of increased sensitivity (specifically,...