Synthesis and Antibacterial Evaluation of Mannich Bases Derived from 1,2,4‐Triazole

Volume: 16, Issue: 10
Published: Sep 6, 2019
Abstract
The series of novel Mannich bases were synthesized and evaluated for their in vitro antibacterial activity against Gram-positive and Gram-negative bacterial strains. The results showed that all compounds were less active than the drugs used as reference, but some of them had moderate potency against Staphylococcus epidermidis ATCC 12228 and Bacillus subtilis ATCC 6633. The presence of a phenyl ring in the position 4 of piperazine seems to be...
Paper Details
Title
Synthesis and Antibacterial Evaluation of Mannich Bases Derived from 1,2,4‐Triazole
Published Date
Sep 6, 2019
Volume
16
Issue
10
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