Neuroprotection and immunomodulation of progesterone in the gut of a mouse model of Parkinson's disease

Volume: 32, Issue: 1
Published: Sep 10, 2019
Abstract
Gastrointestinal symptoms appear in Parkinson's disease patients many years before motor symptoms, suggesting the implication of dopaminergic neurones of the gut myenteric plexus. Inflammation is also known to be increased in PD. We previously reported neuroprotection with progesterone in the brain of mice lesioned with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and hypothesised that it also has neuroprotective and immunomodulatory...
Paper Details
Title
Neuroprotection and immunomodulation of progesterone in the gut of a mouse model of Parkinson's disease
Published Date
Sep 10, 2019
Volume
32
Issue
1
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