Intervening for tricuspid regurgitation: uncertainties in a heterogeneous syndrome

Tricuspid regurgitation (TR) is one of the most common valvular heart lesions encountered in clinical practice. It has now been unequivocally established that the presence of worsening TR is associated with poor outcomes.1 In the past, intervention for severe TR has been infrequently performed due to the lack of prospective data supporting an improvement in outcomes as well as a high reported operative mortality (up to 8%–20%).2 This has...