Reader response: SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy

To move a condition from its genetic definition to a comprehensive syndrome description is an important step forward, and Vlaskamp et al.1 can be thanked for having done this for SYNGAP1 . The inclusion of 57 patients in a multicenter study provided an excellent, detailed delineation of the seizure syndrome. Attention is drawn to some reflex epileptic traits, including seizures precipitated by eating. In a recent study,2 we have particularly...