Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations.
Abstract
Latency reversal agents (LRAs) have proven to induce HIV-1 transcription in vivo but are ineffective at decreasing the size of the latent reservoir in antiretroviral treated patients. The capacity of the LRAs to perturb the viral reservoir present in distinct subpopulations of cells is currently unknown. Here, using a new RNA FISH/flow ex vivo viral reactivation assay, we performed a comprehensive assessment of the viral reactivation capacity of...
Paper Details
Title
Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations.
Published Date
Aug 19, 2019
Journal
Volume
15
Issue
8
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