New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling
Abstract
Harnessing the translational potential of the GLP-1/GLP-1R system in pancreatic beta cells has led to the development of established GLP-1R-based therapies for the long-term preservation of beta cell function. In this review, we discuss recent advances in the current research on the GLP-1/GLP-1R system in beta cells, including the regulation of signaling by endocytic trafficking as well as the application of concepts such as signal bias,...
Paper Details
Title
New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling
Published Date
Mar 1, 2020
Journal
Volume
432
Issue
5
Pages
1347 - 1366
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Notes
History