A Delicate Balance between Bacterial Iron and Reactive Oxygen Species Supports Optimal C. elegans Development
Abstract
Iron is an essential micronutrient for all forms of life; low levels of iron cause human disease, while too much iron is toxic. Low iron levels induce reactive oxygen species (ROS) by disruption of the heme and iron-sulfur cluster-dependent electron transport chain (ETC). To identify bacterial metabolites that affect development, we screened the Keio Escherichia coli collection and uncovered 244 gene deletion mutants that slow Caenorhabditis...
Paper Details
Title
A Delicate Balance between Bacterial Iron and Reactive Oxygen Species Supports Optimal C. elegans Development
Published Date
Sep 1, 2019
Journal
Volume
26
Issue
3
Pages
400 - 411.e3
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