Adenovirus early region 3 RIDα protein limits NFκB signaling through stress-activated EGF receptors
Abstract
The host limits adenovirus infections by mobilizing immune systems directed against infected cells that also represent major barriers to clinical use of adenoviral vectors. Adenovirus early transcription units encode a number of products capable of thwarting antiviral immune responses by co-opting host cell pathways. Although the EGF receptor (EGFR) was a known target for the early region 3 (E3) RIDα protein encoded by nonpathogenic group C...
Paper Details
Title
Adenovirus early region 3 RIDα protein limits NFκB signaling through stress-activated EGF receptors
Published Date
Aug 19, 2019
Journal
Volume
15
Issue
8
Pages
e1008017 - e1008017
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