Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease
Abstract
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease. More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as exosomes, may mediate paracrine and endocrine communication between different tissues and thus modulate gene expression and the function of distal cells. When impaired, these processes can lead to tissue dysfunction, aging, and disease. Adipose tissue is an especially...
Paper Details
Title
Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease
Published Date
Oct 1, 2019
Journal
Volume
30
Issue
4
Pages
656 - 673
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