Pan‐Trk immunohistochemistry is a sensitive and specific ancillary tool for diagnosing secretory carcinoma of the salivary gland and detecting ETV6–NTRK3 fusion

Aims Secretory carcinoma (SC) of the salivary gland typically harbours ETV6 – NTRK3 fusion, which can be utilised clinically to assist with diagnosis. Pan‐Trk inhibitor therapy has demonstrated drastic responses in patients with NTRK ‐translocated tumours, including SC. Pan‐Trk immunohistochemistry (IHC) is emerging as a sensitive and specific tool for detecting NTRK1 , NTRK2 and NTRK3 fusions in various cancers. We aimed to establish the...