Early and reversible changes to the hippocampal proteome in mice on a high-fat diet
Abstract
The rise in global obesity makes it crucial to understand how diet drives obesity-related health conditions, such as premature cognitive decline and Alzheimer’s disease (AD). In AD hippocampal-dependent episodic memory is one of the first types of memory to be impaired. Previous studies have shown that in mice fed a high-fat diet (HFD) episodic memory is rapidly but reversibly impaired. In this study we use hippocampal proteomics to investigate...
Paper Details
Title
Early and reversible changes to the hippocampal proteome in mice on a high-fat diet
Published Date
Aug 23, 2019
Journal
Volume
16
Issue
1
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