Primaquine derivatives: Modifications of the terminal amino group

Volume: 182, Pages: 111640 - 111640
Published: Nov 1, 2019
Abstract
Numerous modifications of the well-known antimalarial drug primaquine, both at the quinoline ring and at the primary amino group, have been reported, mostly to obtain antimalarial agents with improved bioavailability, reduced toxicity and/or prolonged activity. Modifications of the terminal amino group were made with the main idea to prevent the metabolic pathway leading to inactive and toxic carboxyprimaquine (follow-on strategy), but also to...
Paper Details
Title
Primaquine derivatives: Modifications of the terminal amino group
Published Date
Nov 1, 2019
Volume
182
Pages
111640 - 111640
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.