Off-label uses of denosumab in metabolic bone diseases
Abstract
Denosumab (Dmab), a monoclonal antibody against the receptor activator of nuclear factor-κB (RANK) ligand (RANKL) which substantially suppresses osteoclast activity, has been approved for the treatment of common metabolic bone diseases, including postmenopausal osteoporosis, male osteoporosis, and glucocorticoid-induced osteoporosis, in which the pathway of the RANK/RANKL/osteoprotegerin is dysregulated. However, the imbalance of...
Paper Details
Title
Off-label uses of denosumab in metabolic bone diseases
Published Date
Dec 1, 2019
Journal
Volume
129
Pages
115048 - 115048
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